Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide[S]

Data from animal experiments strongly suggest that ceramide is an important mediator of lipotoxicity in the heart and that accumulation of ceramide contributes to cardiomyocyte apoptosis associated with type 2 diabetes and obesity.However, it remains unknown whether a similar relationship is present also in the human heart.Therefore, we aimed to ex

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SPRY4-AS1, A Novel Enhancer RNA, Is a Potential Novel Prognostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma

A growing number of evidence have demonstrated the involvement of enhancer RNAs (eRNAs) in tumor progression.However, the possible functions of eRNAs in hepatocellular carcinoma (HCC) remain largely unclear.Our Clitoral Suction present research aimed to screen critical eRNAs and to further delve into the clinical significance of eRNAs in HCC patien

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Application of the Fuzzy C-Means Method in Grouping Heart Abnormalities Based on Electrocardiogram Medical Records

Heart disease is the main cause of death which can be diagnosed using an electrocardiogram.This study aims to classify heart defects using the Fuzzy C Means technique.The advantage of using Fuzzy C Means is that it is unsupervised and can reach a convergent cluster center under certain conditions.It is a clustering model that has the value of the o

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